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Table 4 Serum concentrations of FABP4 at admission prediction of poor outcomes and mortality with AUROC

From: The association between serum adipocyte fatty acid–binding protein and 3-month disability outcome after aneurysmal subarachnoid hemorrhage

End points

AUROC

 

FABP4

Risk factors a

Risk factors with FABP4 a

Incremental area (P)b

NRI (P)

IDI (P)

Poor outcomes

0.737

0.794

0.818

0.024 (0.01)

0.201 (0.003)

0.022 (0.02)

Mortality

0.709

0.779

0.794

0.015 (0.03)

0.178 (0.009)

0.018 (0.08)

  1. IDI integrated discrimination improvement, NRI net reclassification improvement, CI confidence interval, APACHE-II 5 Acute Physiology and Chronic Health Evaluation II, IVH intraventricular hemorrhage, DCI delayed cerebral ischemia, CRP C-reactive protein, TCD transcranial Doppler, H-H Hunt–Hess
  2. aIncluded those significant risk factors which confirmed in the multivariate analysis (Table 2), including age, surgical clip, coiling, complications in the study, H-H score, aneurysm size > 10 mm, APACHE-II score, IVH sum score, hydrocephalus, cerebral vasospasm, DCI, and CRP
  3. bComparison of AUROCs: established risk factors without FABP4 levels vs. established risk factors with FABP4 levels
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Journal of Neuroinflammation

ISSN: 1742-2094