End points | AUROC | |
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FABP4 | Risk factors a | Risk factors with FABP4 a | Incremental area (P)b | NRI (P) | IDI (P) |
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Poor outcomes | 0.737 | 0.794 | 0.818 | 0.024 (0.01) | 0.201 (0.003) | 0.022 (0.02) |
Mortality | 0.709 | 0.779 | 0.794 | 0.015 (0.03) | 0.178 (0.009) | 0.018 (0.08) |
- IDI integrated discrimination improvement, NRI net reclassification improvement, CI confidence interval, APACHE-II 5 Acute Physiology and Chronic Health Evaluation II, IVH intraventricular hemorrhage, DCI delayed cerebral ischemia, CRP C-reactive protein, TCD transcranial Doppler, H-H Hunt–Hess
- aIncluded those significant risk factors which confirmed in the multivariate analysis (Table 2), including age, surgical clip, coiling, complications in the study, H-H score, aneurysm size > 10 mm, APACHE-II score, IVH sum score, hydrocephalus, cerebral vasospasm, DCI, and CRP
- bComparison of AUROCs: established risk factors without FABP4 levels vs. established risk factors with FABP4 levels