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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

Fig. 4

Effects of exo/miR-193b-3p on putative mRNA target expression. a–d qRT-PCR analysis and western blot analysis showed the expression levels of class I HDACs (Hdacs 1, 2, 3, 8) at 12, 24, 48, and 72 h after SAH (n = 6). e Western blot analysis showed the expression levels of HDAC3 at 12, 24, 48, and 72 h after SAH (n = 6). f, g Changes in expression of Hdac3 and Rela mRNA in the brain tissues of Exos/miR-193b-3p- or Exos/Scr-treated mice were assessed (n = 6). h Expression levels of HDAC3 as well as quantifications in each group. i Western blot analysis of the protein level of ac-p65 in nuclear protein. The data were normalized to β-actin or p65 expression and were expressed as mean ± SD (*p < 0.05, **p < 0.01, and ***p < 0.001)

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Journal of Neuroinflammation

ISSN: 1742-2094