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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

Fig. 5

Exo/miR-193b-3p treatment suppressed apoptosis parameters and decreased levels of the inflammatory cytokines IL-1β, IL-6, and TNF-α after SAH. a–e Changes in expression of Bcl-2, caspase-3, IL-1β, IL-6, and TNF-α in the SAH model as assessed by qRT-PCR. The data were normalized to β-actin expression and expressed as mean ± SD (**p < 0.01, ***p < 0.001, and NS: not significant; n = 6). f–h The results of ELISA for levels of the inflammatory factors IL-1β, IL-6, and TNF-α in mouse brain tissues, n = 6 (***p < 0.001)

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