Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury

Fig. 3

CCL1 released by ODN 2088-treated astrocytes mediates the chemotaxis of peritoneal macrophages. Quantification of F4/80+ cells that crossed to the lower surface of the membrane in response to CM derived from vehicle- or ODN 2088-treated TLR9 astrocytes in the absence or presence of CCL1 neutralizing antibody or IgG2A isotype control [F (5, 48) = 81.03, p < 0.0001 by one-way ANOVA, ****p < 0.0001 by Tukey’s post hoc test]. The results of three independent experiments (n = 3) are shown. Data are presented as mean ± SEM

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094