Fig. 7

Correlation analysis among pathological, ethological, and inflammatory factors. a Shows the coefficient of Pearson correlation analysis between all detected factors. The average of factors in P301S male, P301S female, WT male, and WT female at each time points were applied for calculation. Both r > 0.8 or r < − 0.8 were taken as high relativity. b Shows the results of Pearson correlation coefficient calculated individually. In the scatter diagram, the blue point represents males and red represents females. Because the concentration of plasma human total tau was detected using a mixed sample, we still calculated the correlation coefficients with average data of all parameters compared to other factors