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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord

Fig. 5

Spinal Peli1 knockdown inhibits CCI-induced neuronal activation on the ipsilateral side of the dorsal horn. a Representative images of c-Fos (red) and NeuN (green) in the ipsilateral dorsal horn. b Peli1 shRNA decreases the number of c-Fos positive neurons on day 7 after CCI (scale bar 50 μm, n = 4). One-way ANOVA (F3,12 = 25.2). Results are expressed as the Mean ± SEM. ***p < 0.001 compared with indicated group

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