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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection

Fig. 8

Human astrocytes protect neurons from TBEV infection. Unsorted cells (Uns-C) and enriched neurons (En-N) were infected with TBEV (MOI 10−2) and co-immunostained using anti-βIII-tubulin and anti-TBEV-E3 antibodies. a Percentage of infected neurons among the neuronal population. Manual enumeration. Data are expressed as the mean ± SD. b Immunofluorescence staining of neurons (green). Nuclei were stained with DAPI (blue). Scale bar = 20 μm. Results are representative of two independent experiments performed in triplicate. Statistical analyses were performed with Graphpad Prism V6.0.1 using a two-tailed unpaired t test, **p < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094