Table 1 Differential expression of genes involved in the human antiviral response in unsorted cultures (Uns-C), enriched neurons (En-N), and enriched astrocytes (En-As). Up- and downregulated genes appear in bold, after application of a cut-off of 3
Gene name | Fold regulation | ||
|---|---|---|---|
Uns-C | En-Ne | En-As | |
CXCL10 | 1024.0 | 415.9 | 1209.3 |
MX1 | 367.1 | 39.1 | 975.5 |
CCL5 | 680.3 | 265.0 | 814.6 |
IFNB1 | 149.1 | 71.5 | 537.5 |
OAS2 | 215.3 | 23.9 | 498.0 |
CXCL11 | 270.6 | 126.2 | 388.0 |
ISG15 | 61.8 | 31.8 | 105.4 |
IFIH1 | 32.7 | 19.7 | 35.3 |
DHX58 | 13.2 | 10.6 | 28.2 |
CASP1 | 10.5 | 6.3 | 24.6 |
CXCL8 | 28.4 | 11.4 | 23.1 |
DDX58 | 10.5 | 5.7 | 16.0 |
IL6 | 7.4 | 10.6 | 8.2 |
STAT1 | 5.8 | 2.5 | 7.5 |
TLR3 | 6.2 | 1.7 | 6.4 |
IRF7 | 5.0 | 0.9 | 5.3 |
CTSS | 4.3 | 1.3 | 5.2 |
TRIM25 | 3.6 | 2.2 | 4.5 |
AIM2 | 0.9 | 1.0 | 4.0 |
MYD88 | 2.4 | 1.1 | 3.7 |
TNF | 4.5 | 2.6 | 3.7 |
IL15 | 3.8 | 3.3 | 2.3 |
IFNA1 | 0.9 | 3.6 | 1.2 |
IL12B | 0.9 | 5.9 | 1.2 |