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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice

Fig. 1

Diet rich in microbiota-accessible carbohydrate prevented gut microbiota dysbiosis in diet-induced obese mice. a Levels of fecal bacterial DNA were quantitated by qPCR (n = 6). Cecal contents of microbiota composition were analyzed by 16S RNA sequencing (n = 5–7) (b–j). b Principal coordinates analysis plot of bray distances. c–e The α-diversity of the fecal microbiome among three groups depicted according to Chao index (c), ACE index (d), and Shannon index (e). f Composition of abundant bacterial phyla. g Ratio of Firmicutes (FM) to Bacteroidetes (BO). h Linear discriminant analysis (LDA) effect size showing the most differentially significant abundant taxa enriched in microbiota from the control (Con) vs. HF-FD vs. HF-MAC. i Cladogram generated from linear discriminant analysis (LDA). Values are mean ± SEM. *p < 0.05 vs. Con. #p < 0.05 vs. high-fat and fiber-deficient (HF-FD). p, phylum

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