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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury

Fig. 3

MicroRNA microarray analysis of exosomes released from Ext-stimulated astrocytes. a CON: exosomes secreted by astrocytes under physiological conditions. COR: exosomes secreted by astrocytes under simulated trauma. The miRNA component of the exosomes released from stimulated astrocytes was studied by microRNA microarray analysis. The heat map shows the change of the first 20 miRNAs. b The miRNA distribution diagram. The transverse axis represents multiple miRNAs in the Ext group compared to those in the CON group, and the longitudinal axis represents the Log10 of the p value. c The expression of miR-873a-5p in necrotic brain tissue and oedema brain tissue in traumatic brain injury was measured by RT-PCR (data were presented as mean ± SD, compared with the oedema area group, **p < 0.01, n = 15, t test)

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Journal of Neuroinflammation

ISSN: 1742-2094