Fig. 8

The in vivo effects of miR-873a-5p on NF-κB activation in mice TBI model. a–d Brain tissue of the in vivo mice TBI model was collected at the seventh day post-TBI. Western blot demonstrating that miR-873a-5p agomir administration suppressed Myd88 signal activation and reversed TBI-induced phosphorylation of NF-κB and ERK (data were presented as mean ± SD, compared with the sham group ****p < 0.0001, compared with the TBI group ^##p < 0.01, ^###p < 0.001, n = 5, one-way ANOVA)