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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke

Fig. 1

DJ-1 interference exacerbated injury after cerebral I/R injury. a HE staining and Nissl staining (× 400). b TTC staining. c Histograms showing the number of intact neurons in the cortex. d Infarct volume in the brain. e Neurological scores. f Cell viability after OGD/R. OGD/R = oxygen-glucose deprivation/reoxygenation. The in vivo groups were as follows: (1) the sham group, (2) the MCAO group, (3) the NC group, and (4) the DJ-1 siRNA group. The in vitro groups were as follows: (1) the control group, (2) the OGD/R group, (3) the NC group, and (4) the DJ-1 siRNA group. The data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. n = 6 per group

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