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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Antinociceptive effect of intrathecal injection of miR-9-5p modified mouse bone marrow mesenchymal stem cells on a mouse model of bone cancer pain

Fig. 5

MiR-9-5p modified BMSCs further inhibited inflammatory response in sarcoma-inoculated mice. ac MiR-9-5p promoted BMSCs’ capability of suppressing TNF-α (a), IL-6 (b), and IL-1β (c) release in ipsilateral dorsal root ganglion at postoperative day 21. df MiR-9-5p promoted BMSCs’ capability of suppressing TNF-α (d), IL-6 (e), and IL-1β (f) mRNA level in ipsilateral dorsal root ganglion at postoperative day 21. qRT-PCR was used to measure the mRNA level. ELISA was used to measure cytokine concentration. In each group, n = 6. Mean ± SD data is used to present all data. *p < 0.05, **p < 0.01, and ***p < 0.001

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