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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: The analgesic action of larixyl acetate, a potent TRPC6 inhibitor, in rat neuropathic pain model induced by spared nerve injury

Fig. 1

The establishment of neuropathic pain model induced by SNI. a The manifestation of the mechanical sensitivity before and after surgery in nerve injured and sham groups. Mechanical thresholds were acquired by von Frey filament test. SNI caused dramatic increase of mechanical sensitivity in the ipsilateral hindpaw from postoperative day (POD) 1 and lasted throughout the follow-up. n = 8. b Illustration of cold sensitivity in SNI and sham groups. SNI rats developed remarkable response to acetone application in the ipsilateral side since POD 1, while this response was actually missing in the sham group. n = 8

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