Fig. 1
DMI ameliorates disease severity in chronic EAE. C57BL/6 mice were immunized with MOG35–55 and administered i.p. with vehicle (n = 15) or 400 mg/kg DMI (n = 20) every day starting from day 3 post-immunization. a The clinical score of EAE animals was followed for a period of 30 days. b The incidence and mortality rate of vehicle- and DMI-treated EAE mice were accessed, and the mean ± SEM of onset of disease, maximum score, and cumulative score (day 1 to day 30 post-immunization) in vehicle- and DMI-treated EAE was also calculated. Statistical significance was determined as *p < 0.05, **p < 0.01, and ***p < 0.001 by Mann-Whitney U test