Western blot analysis for the expression of synaptophysin (a) and PSD-95 (b) in the hippocampus. Values represent the mean ± S.E.M. of 4–7 animals per group. Quantitative protein expression of synaptophysin and PSD-95 bands detected by Western blot using β-actin as a loading control (c). Sham-Sed, sham surgery non-exercised group; Sham-Ex, sham surgery exercised group; 2VO-Sed, chronic cerebral hypoperfusion non-exercised group; 2VO-Ex, chronic cerebral hypoperfusion exercised group. In a *p < 0.05 vs. Sham-Sed and #p < 0.05 vs. 2VO-Sed (unpaired Student’s t test); in b #p = 0.0556 vs. 2VO-Sed (unpaired Student’s t test).