Fig. 2
From: Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits
GA disturbs neuronal iron metabolism. Western blot analysis of iron-related proteins including IRP2 (iron regulatory protein 2), TfR1 (an iron uptake protein), and ferritin (an iron storage protein). A representative image set is presented for the cultured hippocampal neurons at DIV 9 (a), the hippocampus of rat pups at PND 8 (b), and the hippocampus of 15-month-old mice (c). The drug treatment is same as in Fig. 1. Data are presented as mean ± SEM (n = 6); *p < 0.05 compared with Con group; #p < 0.05 compared with the GA (Ket or Sev) group