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Table 1 Baseline clinical characteristics of acute stroke patients and healthy controls

From: KLF4 alleviates cerebral vascular injury by ameliorating vascular endothelial inflammation and regulating tight junction protein expression following ischemic stroke

CharacteristicsControls (n = 33)NIHSS < 7 (n = 39)NIHSS ≥ 7 (n = 35)
Age mean ± SD (years)64.92 ± 9.1665.41 ± 10.0367.54 ± 12.57
Male, n (%)19 (57.58%)25 (64.1%)24 (68.57)
Hypercholesterolemia, n (%)9 (27.27%)20 (51.28%)*19 (54.29%)*
Hypertension, n (%)15 (45.45%)26 (66.67%)26 (74.29%)*
Diabetes, n (%)4 (12.12%)11 (28.21%)12 (34.29%)
Active smoker, n (%)8 (24.24%)10 (25.64%)15 (42.86%)
Alcohol, n (%)5 (15.15%)8 (20.51%)13 (37.14%)
Atrial fibrillation, n (%)3 (9.09%)6 (15.38%)11 (31.43%)*
Coronary disease, n (%)3 (7.69%)5 (14.26%)
Previous antiplatelet treatment, n (%)10 (30.3%)12(30.77%)13(37.14%)
Previous treatment with statin, n (%)9 (27.27%)14 (35.9%)15 (42.86%)
  1. Minor stroke was defined as NIHSS score < 7, moderate to severe stroke defined as NIHSS score ≥ 7
  2. NIHSS National Institute of Health Stroke Scale, SD standard deviation
  3. *P < 0.05 vs healthy controls