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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats

Fig. 10

Upregulation of TNF-α, p-p65, and IL-1β in the hippocampus was reversed by L-TAMS. The expression of TNF-α, p-p65, and IL-1β were all found to be increased on day 20 after the first CYP injection. The expression of the three proteins in the cystitis group treated with L-TAMS was significantly lower than that in the untreated cystitis group. No significant difference was observed between the CYP + L-TAMS group and Veh group. **P < 0.01 and ***P < 0.001 vs. Veh group, ##P < 0.01 and ###P < 0.001 vs. CYP group. Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test

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