Fig. 2

PKO mice show enhanced neuronal cell death and exacerbated BBB disruption after ICH. a Representative images of FJC-stained control and PKO brains from sham group and at D2, D5, and D14 after ICH. b Quantification of FJC⁺ cells in control and PKO mice. *p < 0.05, compared to controls at the same time points (Student’s t test), n = 3–4. c, d Quantifications of FITC-Dextran (c) and Evans blue (d) leakage in control and PKO brains from sham group and at D2, D5, and D14 after ICH. *p < 0.05, compared to controls at the same time points (ANOVA followed by Newman-Keuls test), n = 8–14 in (c) and n = 6–11 in (d). Data are shown as mean ± SD