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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection

Fig. 2

Pro-inflammatory mediator production during S. aureus craniotomy infection is primarily TLR2-dependent. WT and TLR2 KO mice were sacrificed at days 7 or 14 following S. aureus craniotomy infection, whereupon (a) IL-1β, (b) CCL2, (c) G-CSF, (d) IFN-γ, (e) TNF-α, (f) IL-6, (g) CXCL2, and (h) IL-17 production was quantified using Milliplex multi-analyte bead arrays. Results were combined from two independent experiments (n = 5–10 mice/group) and analyzed by one-way ANOVA with Tukey’s multiple comparison test (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)

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Journal of Neuroinflammation

ISSN: 1742-2094