Fig. 5From: TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infectionCaspase-1 is important for S. aureus containment in the galea and brain during craniotomy infection. WT and caspase-1 (Casp-1) KO mice were sacrificed at days 3, 7, or 14 following S. aureus craniotomy infection, whereupon bacterial burden in the galea, brain, and bone flap was quantified. Results were combined from 3 independent experiments (n = 10–20 mice/group) and analyzed by unpaired Student’s t test (**p < 0.01, ***p < 0.001)Back to article page