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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection

Fig. 9

TLR2 limits tissue damage during S. aureus craniotomy infection. WT, TLR2 KO, and caspase-1 (Casp-1) KO mice were sacrificed at day 7 following S. aureus craniotomy infection, whereupon cryosections of the head were processed for H&E staining to visualize the extent of inflammation in the galea and brain. Images presented are representative of 3 mice/group (× 2 magnification; scale bar = 1 mm). Arrows depict the bone flap, and the extent of brain parenchymal damage is denoted with dashed lines

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