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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage

Fig. 7

Western blot of rDKK3/Kremen-1/DVL-1 mechanistic pathway. Representative western blot bands (a) and the densitometric quantification of DKK3 (b), Kremen-1 (c), DVL-1 (d), p-JNK (e), AP-1 (F), cleaved caspase-1 (g), and IL-1β (h) in the sham, vehicle, rDKK3, rDKK3 + scrambled siRNA, rDKK3 + Kremen-1 siRNA, and rDKK3 + DVL-1 siRNA groups 24 h after ICH. Data are expressed as the mean ± SD. *p < 0.05 versus sham; #p < 0.05 versus vehicle; @p < 0.05 vs rDKK3 + scramble siRNA group, n = 6 animals per group

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Journal of Neuroinflammation

ISSN: 1742-2094