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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model

Fig. 9

Effects of NLRP1 activation CRISPR on downstream proteins in proposed signaling pathway with STF083010 treatment at 48 h post HI. a Representative pictures of the western blot bands of the proteins NLRP1, cleaved caspase-1(CC1), IL-1β, and IL-18. be Quantitative analysis of the relative expression level of proteins NLRP1, cleaved caspase-1, IL-1β, and IL-18. Data are represented as means ± SD. n = 6 for each group. *P < 0.05 vs. sham group; @P < 0.05 vs. HI + Vehicle; &P < 0.05 vs. HI + STF083010 + CRISPR control

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