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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

Fig. 6

Transcript response to lipopolysaccharide (LPS) in the amygdala and hippocampus of adult males. a, b Heatmaps represent transcript levels in the amygdala and hippocampus for individual animals. c–e Relative transcript abundance of IκBα (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha), IL6 (interleukin 6), and MKP1 (mitogen activated protein kinase phosphatase 1) in the amygdala. f–j Relative transcript abundance of IκBα, IL6, CD11B (cluster of differentiation molecule 11B), MKP1, and IGF1 (insulin-like growth factor 1) in the hippocampus. Data presented are means ± standard error. n = 6/experimental group. Main effect of challenge: *p < 0.05. Main effect of diet: **p < 0.05. Diet/challenge interaction: ***p < 0.05. Scheffe post hoc testing was used for pairwise comparisons (p < 0.05)

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Journal of Neuroinflammation

ISSN: 1742-2094