Fig. 3From: PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human studyWhole brain time-activity curves of [11C]MC1 uptake before (a) and on day 1 after the first lipopolysaccharide (LPS) injection (b) in monkey 2, under baseline and blocked conditions by MC1 (0.3 mg/kg, i.v.) on the same day. LPS increased whole brain [11C]MC1 uptake, which was blocked by cold parentBack to article page