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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3

Fig. 4

Effects of lncGBP9 on macrophage polarization in vivo. LncGBP9 silencing was conducted in the SCI mice model via tail vein injection Ad-sh-lncGBP9. n = 5 in each group. a The in vivo infection efficiency was verified by real-time PCR. b The BMS scores were evaluated on days 1, 3, 7, 14, and 28 after operation (n = 5). c, d The content and distribution of M1 macrophage marker CD16/32 and M2 macrophage marker Arg1 determined by IF staining on day 28 after operation (n = 5). e The protein levels of STAT1, p-STAT1, STAT6, p-STAT6, and SOCS3 determined by Immunoblotting on day 28 after operation (n = 3). **P < 0.01

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