Fig. 7
From: MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia
Graphical summary of results. Increased LPA levels generated via the ATX or cPLA2 pathways promote a distinct pro-inflammatory phenotype in microglia via LPAR signal transmission. Interference with the three MAPK signaling pathways regulated the LPA-induced inflammatory state in different ways. The individual steps between LPARs and MAPKs are not presented in the graph since these parts of the pathways were not experimentally addressed during the present study