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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier

Fig. 6

Impact of RRMS sera treatment on the mitochondria content and membrane potential in brain ECs. (a, b) Representative flow cytometry plots and cumulative graphs of mitotracker green staining in hCMEC/D3 cells treated with 20% RRMS sera or HD for 16 h. (c, d) Representative flow cytometry plots and cumulative graphs of TMRE staining showing membrane potential in hCMEC/D3 treated with RRMS or HD sera. Data are expressed as mean ± s.e.m. of 30 donors/group (pooled in pairs matched in sex, age and EDSS score for RRMS patients). Statistical analysis by Mann-Whitney U test (two-tails) **P ≤ 0.01

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