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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: The neuroregenerative effects of topical decorin on the injured mouse cornea

Fig. 3

Experiment 1: Changes to corneal immune cells after 1 week of topical treatment, dosed 3 times/day. ac Representative confocal images of the anterior stromal CD45+ Iba1+ macrophages in the central cornea of naïve (a1–a4), saline-treated (b1–b4) or decorin-treated eye (c1–c4). Scale bar in c4 (50 μm) applies to all images. d, e Density of anterior stromal macrophages in the central and peripheral cornea. f, g Density of epithelial DCs in the central and peripheral cornea. Summary data are shown as mean ± SD. Each data point represents a single cornea. Red symbols represent the contralateral eye of the decorin-treated eye. Asterisk indicates a statistically significant difference between eyes with and without decorin treatment. P values for each of the inter-group comparisons are provided in Table 1. Legend: DCN, decorin; Gel, fluid gel

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