Table 2 Experiment 2: Comparison of immune cell densities in eyes with different topical treatments after 6 h (i.e., 3× doses, 2 h apart)
From: The neuroregenerative effects of topical decorin on the injured mouse cornea
| Â | Main effects | Interactions | ||||||
|---|---|---|---|---|---|---|---|---|
Decorin | Fluid gel | Contralateral eye effect | Decorin # Gel | Gel # Contralateral | ||||
Contrast (95% CI) | p value | Contrast (95% CI) | p value | Contrast (95% CI) | p value | p value | p value | |
Re-epithelialisation (%) | 2.4 (− 3.1, 8.0) | 0.377 | − 3.9 (− 9.9, 2.1) | 0.192 | 0.1 (− 5.5, 5.7) | 0.977 | 0.982 | 0.878 |
Stromal thickness (μm) | − 0.8 (− 9.8, 8.1) | 0.854 | 16.5 (7.1, 26.0) | 0.002 | 2.5 (− 6.4, 11.3) | 0.573 | 0.204 | 0.153 |
Peripheral cornea | Â | Â | Â | Â | Â | Â | Â | Â |
 DCs (cells/mm2) | 15.7 (7.6, 23.8) | < 0.001 | − 4.6 (− 13.0, 3.7) | 0.261 | 3.4 (− 4.7, 11.5) | 0.400 | 0.200 | 0.248 |
 DC area (μm2/cell) | 119.3 (− 68.8, 307.4) | 0.205 | − 172.6 (− 369.7, 24.5) | 0.083 | 137.1 (− 51.0, 325.2) | 0.147 | 0.460 | 0.302 |
 Macrophages (cells/mm2) | − 6.9 (− 23.4, 9.5) | 0.396 | − 0.2 (− 18.0, 17.5) | 0.977 | − 10.4 (− 26.9, 6.1) | 0.206 | 0.196 | 0.832 |
 Neutrophils (cells/mm2) | − 144.5 (− 343.9, 54.9) | 0.150 | − 135.4 (− 342.3, 71.5) | 0.188 | − 281.1 (− 480.5, − 81.8) | 0.007 | 0.071 | 0.317 |