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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke

Fig. 4

CSF1R KD improved survival. a CSF1R animals experienced a 22.2% mortality post-stroke, while the NTC animals experienced a 37.5% mortality. b Stroke in both NTC and CSF1R KD animals resulted in increased BG. c Body weight steadily increased over time in all groups. When all three groups compared, body weight was significantly different between the groups (p = 0.0156). However, there was no difference in percent body weight change in NTC and CSF1R KD groups that were subjected to stroke as compared to sham animals. d The adhesive removal task (ART) was utilized to measure sensorimotor function. Overall, there was an improvement in latency over 3 weeks (p = 0.013) and there was no significant difference between the NTC and CSF1R KD animals (N = 5–7/group)

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