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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease

Fig. 2

Boc2 treatment ameliorates neuronal loss in APP/PS1 double-transgenic mice. a Coronal brain sections of 29-week-old APP/PS1 double-transgenic or WT mice with or without Boc2 treatment were stained with anti-NeuN antibodies to label neuronal cells. Representative images of the cortex (left) and hippocampus (right) are shown. Quantification of NeuN-staining of the (b) layer V (cell density/mm2) or (c) dentate gyrus of the hippocampus (fluorescence intensity %). Statistical significance was determined using Kruskal-Wallis followed by Dunn post hoc test (B/C). Data represent mean + SEM; n ≥ 5; *p < 0.05, ***p < 0.001

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