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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease

Fig. 6

Boc2-treatment increases the expression of Aβ-degrading enzymes in APP/PS1 double-transgenic mice. (a, b) insulin-degrading enzyme (Ide) and (c, d) neprilysin (Nep) mRNA expression in the hippocampus and cortex of 29-week-old APP/PS1 double-transgenic mice or WT mice with or without Boc2 treatment. Statistical significance was determined using two-way ANOVA with turkey test. Data represent mean + SEM; n ≥ 6; *p < 0.05, **p < 0.01, ***p < 0.001 as indicated

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