Fig. 4

Glybenclamide suppresses NLRP3 inflammasome activation in P + M-treated mice. a The expressions of NLRP3, caspase-1, and IL-1β in the brainstem of P + M-treated mice with or without glybenclamide (Gly) were detected by using Western blot, and the representative blots were shown. GAPDH was used as an internal control. b–d The band density of NLRP3 (b), caspase-1 p10 (c), and IL-1β (d) was quantified. n = 6 for each group. *p < 0.05. **p < 0.01