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Table 11 CSF findings during acute attacks (first LP/event) and during remission (last LP/event)

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

  Units Attack, all, first LP/event Remission, all, last LP/event p values
Pleocytosis Samples 54/102 (52.9%) 2/20 (10%) p = 0.0004
WCC Cells/μl 6.5 (0-463; 100) 2 (0-16; 19) p < 0.0002
WCC > 100/μl Samples 13/101 (12.9%) 0/20 (0%) p = n.s.
OCB Samples 9/96 (9.4%) 2/20 (10%) p = n.s.
QIgG > Qlim(IgG) Samples 6/85 (7.1%) 1/18 (5.6%) p = n.s.
QIgG Ratio 3.47 (0.9-23.61; 84) 2.66 (1.47-6.7; 18) p = n.s.
IgG-IF > 10% Samples 4/84 (4.8%) 0/18 (0%) p = n.s.
QIgM > Qlim(IgM) Samples 11/73 (15.1%) 0/15 (0%) p = n.s.
QIgM Ratio 0.59 (0-13.81; 72) 0.3 (0-1.36; 15) p < 0.03
QIgA > Qlim(IgA) Samples 3/72 (4.2%) 1/15 (6.7%) p = n.s.
QIgA Ratio 1.76 (0-17.27; 71) 1.94 (0-4.83; 15) p = n.s.
QAlb > Qlim(Alb) Samples 42/88 (47.7%) 5/18 (27.8%) p = n.s.
QAlb Ratio 6.46 (2.98-32.67; 88) 5.55 (3.13-15.33; 18) p = n.s.
CSF TP elevated Samples 42/93 (45.2%) 5/20 (25%) p = n.s.
CSF TP concentration mg/dl 44.5 (20.5-176; 85) 36.65 (5.11-101; 18) p = n.s.
CSF TP > 100 mg/dl Samples 7/93 (7.5%) 1/20 (5%) p = n.s.
CSF l-lactate elevated Samples 16/65 (24.6%) 0/15 (0%) p = 0.033
CSF l-lactate concentration mg/dl 1.82 (1.05-4.43; 62) 1.7 (1.33-2.1; 14) p = n.s.
CSF l-lactate > 3 mmol/l Samples 4/65 (6.2%) 0/15 (0%) p = n.s.
Time since attack onset Days 8 (0-34; 104) 191 (117-2624; 20)  
  1. Ratios and concentrations are given as median (with ranges and sample numbers in brackets)
  2. IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein