| |
Units
|
Total
|
Attack
|
Remission
|
Acute MY subgroup
|
Acute ON subgroup
|
Acute BRAIN subgroup
|
|---|
|
Blood-CSF barrier function
|
|
QAlb > QAlb(lim)
|
Samples
|
67/139 (48.2%)
|
49/105 (46.7%)
|
10/23 (43.5%)
|
28/50 (56%)
|
16/46 (34.8%)
|
4/8 (50%)
|
|
QAlb, all LPs
|
-
|
6.6 (3-32.7; 138)
|
6.4 (3-32.7; 105)
|
6 (3.1-18.5; 23)
|
7.4 (3.1-32.7; 50)
|
5.4 (3-26.3; 46)
|
7.8 (3.6-8.9; 8)
|
|
QAlb, if positive
|
-
|
9.6 (5.5-32.67; 66)
|
9.2 (5.5-32.67; 49)
|
11.8 (8.08-18.51; 10)
|
10.8 (6.4-32.7; 28)
|
7.8 (5.5-26.3; 16)
|
8 (6.8-8.9; 4)
|
|
Alb CSF
|
mg/l
|
273 (123-1260; 131)
|
261.5 (123-1260; 98)
|
280 (123-694; 22)
|
305 (133-1038.9; 46)
|
218 (123-1260; 43)
|
310 (175-371; 8)
|
|
Alb serum
|
g/l
|
42.1 (25.9-50.6; 126)
|
42.15 (25.9-50.6; 94)
|
41.8 (33.5-49.8; 22)
|
42.2 (25.9-50.6; 46)
|
42.2 (32.4-50.4; 39)
|
41.9 (37.3-48.7; 8)
|
|
Albumin-cellular dissociation
|
Samples
|
23/67 (34.3%)
|
14/49 (28.6%)
|
4/10 (40%)
|
2/28 (7.1%)
|
11/16 (68.8%)
|
1/4 (25%)
|
|
Combined BCB disruption
|
|
and intrathecal IgG synthesis
|
Samples
|
12/67 (17.9%)
|
8/49 (16.3%)
|
1/10 (10%)
|
6/28 (21.4%)
|
1/16 (6.3%)
|
1/4 (25%)
|
|
CSF total protein
|
|
CSF TP, elevated
|
Samples
|
64/146 (43.8%)
|
49/110 (44.5%)
|
9/25 (36%)
|
27/51 (52.9%)
|
16/50 (32%)
|
6/8 (75%)
|
|
CSF TP, all LPs
|
mg/dl
|
43.75 (5.11-176; 136)
|
43.75 (20.4-176; 102)
|
40 (5.11-148; 23)
|
49.6 (20.5-176; 48)
|
37.2 (20.4-171.8; 46)
|
48.2 (30.4-74.2; 8)
|
|
CSF TP, if elevated
|
mg/dl
|
64.65 (45.3-176; 64)
|
65 (45.3-176; 49)
|
61.9 (47-148; 9)
|
73.3 (46.7-176; 27)
|
60.4 (45.3-171.8; 16)
|
50.7 (47-74.2; 6)
|
|
CSF TP, > 100 mg/dl
|
Samples
|
11/136 (8.1%)
|
8/102 (7.8%)
|
2/23 (8.7%)
|
7/48 (14.6%)
|
1/46 (2.2%)
|
0/0 (0%)
|
|
CSF l-lactate
|
|
CSF l-lactate, elevated
|
Samples
|
28/107 (26.2%)
|
25/79 (31.6%)
|
1/20 (5%)
|
18/37 (48.6%)
|
7/39 (17.9%)
|
0/3 (0%)
|
|
CSF l-lactate, all LPs
|
mmol/l
|
1.8 (1.05-4.43; 103)
|
1.9 (1.05-4.43; 76)
|
1.7 (1.33-2.4; 19)
|
2.31 (1.12-4.43; 35)
|
1.75 (1.05-2.68; 38)
|
1.51 (1.5-1.7; 3)
|
|
CSF L-lactate, if elevated
|
mmol/l
|
2.68 (2.1-4.43; 28)
|
2.68 (2.1-4.43; 25)
|
2.4 (2.4-2.4; 1)
|
2.53 (1.88-4.43; 20)
|
1.7 (1.05-2.68; 10)
|
1.51 (1.5-1.51; 2)
|
|
CSF l-lactate, >3 mmol/l
|
Samples
|
10/103 (9.7%)
|
8/76 (10.5%)
|
0/19 (0%)
|
8/35 (22.9%)
|
0/38 (0%)
|
0/3 (0%)
|
- Ratios and concentrations are given as median (with ranges and sample numbers in brackets)
- Alb albumin; BCB blood–CSF barrier; LP lumbar puncture; QAlb CSF/serum albumin ratio; TP total protein
