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Table 7 CSF findings at the time of the first LP and at the time of follow-up

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

  Units First LP ever Follow-up LPs, first LP/event
Pleocytosis, all acute attacks Samples 44/79 (55.7%) 10/23 (43.5%)
Pleocytosis, acute MY Samples 26/31 (83.9%) 6/9 (66.7%)
Pleocytosis, acute ON Samples 12/39 (30.8%) 3/11 (27.3%)
Pleocytosis, acute BRAIN Samples 5/7 (71.4%) 1/3 (33.3%)
OCB, all acute attacks Samples 7/73 (9.6%) 2/23 (8.7%)
OCB, acute MY Samples 1/27 (3.7%) 2/10 (20%)#
OCB, acute ON Samples 3/38 (7.9%) 0/10 (0%)
OCB, acute BRAIN Samples 2/7 (28.6%) 0/3 (0%)
IgG-IF > 10%, all acute attacks Samples 4/63 (6.3%) 3/24 (12.5%)
IgG-IF > 10%, acute MY Samples 2/26 (7.7%) 0/9 (0%)
IgG-IF > 10%, acute ON Samples 2/31 (6.5%) 0/9 (0%)
IgG-IF > 10%, acute BRAIN Samples 0/5 (0%) 0/3 (0%)
QAlb > Qlim(Alb), all acute attacks Samples 35/65 (53.8%) 7/23 (30.4%)
QAlb > Qlim(Alb), acute MY Samples 16/26 (61.5%) 6/10 (60%)
QAlb > Qlim(Alb), acute ON Samples 14/33 (42.4%) 1/10 (10%)
QAlb > Qlim(Alb), acute BRAIN Samples 4/5 (80%) 0/3 (0%)
CSF TP elevated, all acute attacks Samples 33/70 (47.1%) 9/23 (39.1%)
CSF TP elevated, acute MY Samples 15/27 (55.6%) 6/10 (60%)
CSF TP elevated, acute ON Samples 14/37 (37.8%) 1/10 (10%)
CSF TP elevated, acute BRAIN Samples 4/5 (80%) 2/3 (66.7%)
CSF l-lactate elevated, all acute attacks Samples 14/52 (26.9%) 2/13 (15.4%)
CSF l-lactate elevated, acute MY Samples 9/21 (42.9%) 1/5 (20%)
CSF l-lactate elevated, acute ON Samples 5/28 (17.9%) 1/8 (12.5%)
CSF l-lactate elevated, acute BRAIN Samples 0/3 (0%) 0/0 (0%)
Time since attack onset, acute LPs Days 7 (0-34) 9.5 (0-28)
  1. To control for the fact that the number of CSF samples obtained per event differed among patients in the subgroup with follow-up LPs, only the first LP obtained during each attack was taken into account for this analysis
  2. IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein; WCC white cell count
  3. #p = n.s.