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Table 7 CSF findings at the time of the first LP and at the time of follow-up

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

 

Units

First LP ever

Follow-up LPs, first LP/event

Pleocytosis, all acute attacks

Samples

44/79 (55.7%)

10/23 (43.5%)

Pleocytosis, acute MY

Samples

26/31 (83.9%)

6/9 (66.7%)

Pleocytosis, acute ON

Samples

12/39 (30.8%)

3/11 (27.3%)

Pleocytosis, acute BRAIN

Samples

5/7 (71.4%)

1/3 (33.3%)

OCB, all acute attacks

Samples

7/73 (9.6%)

2/23 (8.7%)

OCB, acute MY

Samples

1/27 (3.7%)

2/10 (20%)#

OCB, acute ON

Samples

3/38 (7.9%)

0/10 (0%)

OCB, acute BRAIN

Samples

2/7 (28.6%)

0/3 (0%)

IgG-IF > 10%, all acute attacks

Samples

4/63 (6.3%)

3/24 (12.5%)

IgG-IF > 10%, acute MY

Samples

2/26 (7.7%)

0/9 (0%)

IgG-IF > 10%, acute ON

Samples

2/31 (6.5%)

0/9 (0%)

IgG-IF > 10%, acute BRAIN

Samples

0/5 (0%)

0/3 (0%)

QAlb > Qlim(Alb), all acute attacks

Samples

35/65 (53.8%)

7/23 (30.4%)

QAlb > Qlim(Alb), acute MY

Samples

16/26 (61.5%)

6/10 (60%)

QAlb > Qlim(Alb), acute ON

Samples

14/33 (42.4%)

1/10 (10%)

QAlb > Qlim(Alb), acute BRAIN

Samples

4/5 (80%)

0/3 (0%)

CSF TP elevated, all acute attacks

Samples

33/70 (47.1%)

9/23 (39.1%)

CSF TP elevated, acute MY

Samples

15/27 (55.6%)

6/10 (60%)

CSF TP elevated, acute ON

Samples

14/37 (37.8%)

1/10 (10%)

CSF TP elevated, acute BRAIN

Samples

4/5 (80%)

2/3 (66.7%)

CSF l-lactate elevated, all acute attacks

Samples

14/52 (26.9%)

2/13 (15.4%)

CSF l-lactate elevated, acute MY

Samples

9/21 (42.9%)

1/5 (20%)

CSF l-lactate elevated, acute ON

Samples

5/28 (17.9%)

1/8 (12.5%)

CSF l-lactate elevated, acute BRAIN

Samples

0/3 (0%)

0/0 (0%)

Time since attack onset, acute LPs

Days

7 (0-34)

9.5 (0-28)

  1. To control for the fact that the number of CSF samples obtained per event differed among patients in the subgroup with follow-up LPs, only the first LP obtained during each attack was taken into account for this analysis
  2. IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein; WCC white cell count
  3. #p = n.s.