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Table 9 CSF findings in samples from patients with monophasic disease and from patients with relapsing disease

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

1st LP/event Units Monophasic Relapsing
Pleocytosis, acute attacks Samples 17/27 (63%) 37/74 (50%)§
Pleocytosis, acute MY Samples 12/14 (85.7%) 20/26 (76.9%)
Pleocytosis, acute ON Samples 3/9 (33.3%) 12/40 (30%)
Pleocytosis, acute BRAIN Samples 2/4 (50%) 4/6 (66.7%)
OCB, acute attacks Samples 4/25 (16%) 5/70 (7.1%)§
OCB, acute MY Samples 1/12 (8.3%) 2/25 (8%)
OCB, acute ON Samples 1/9 (11.1%) 2/38 (5.3%)
OCB, acute BRAIN Samples 2/4 (50%) 0/6 (0%)
IgG-IF > 10%, acute attacks Samples 1/21 (4.8%) 3/62 (4.8%)§
IgG-IF > 10%, acute MY Samples 1/12 (8.3%) 1/23 (4.3%)
IgG-IF > 10%, acute ON Samples 0/6 (0%) 2/33 (6.1%)
IgG-IF > 10%, acute BRAIN Samples 0/3 (0%) 0/5 (0%)
QAlb > Qlim(Alb), acute attacks Samples 12/21 (57.1%) 30/66 (45.5%)§
QAlb > Qlim(Alb), acute MY Samples 8/12 (66.7%) 14/24 (58.3%)
QAlb > Qlim(Alb), acute ON Samples 2/6 (33.3%) 13/36 (36.1%)
QAlb > Qlim(Alb), acute BRAIN Samples 2/3 (66.7%) 2/5 (40%)
CSF TP elevated, acute attacks Samples 15/24 (62.5%) 27/68 (39.7%)§
CSF TP elevated, acute MY Samples 9/12 (75%) 12/25 (48%)
CSF TP elevated, acute ON Samples 4/9 (44.4%) 11/37 (29.7%)
CSF TP elevated, acute BRAIN Samples 2/3 (66.7%) 4/5 (80%)
CSF l-lactate elevated, acute attacks Samples 7/18 (38.9%) 8/46 (17.4%)§
CSF l-lactate elevated, acute MY Samples 6/10 (60%) 4/16 (25%)
CSF l-lactate elevated, acute ON Samples 1/6 (16.7%) 4/29 (13.8%)
CSF l-lactate elevated, acute BRAIN Samples 0/2 (0%) 0/1 (0%)
Time since attack onset, acute LPs Days 5 (0-31) 9.5 (0-34)
  1. To control for differences in the number of follow-up samples available per patient, only the first LP performed during each acute event was considered
  2. IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein
  3. §p = n.s.