Table 4 Immunoglobulin class response patterns in MOG-IgG-positive EM
| Â | Units | Total | Attack | Remission | Acute MY subgroup | Acute ON subgroup | Acute BRAIN subgroup |
|---|---|---|---|---|---|---|---|
a. Based on QIg > Qlim(Ig) | |||||||
3-class reaction | Samples | 3/63 (4.8%) | 3/56 (5.4%) | 0/5 (0%) | 2/18 (11.1%) | 0/16 (0%) | 1/22 (4.5%) |
2-class reaction | Samples | 12/63 (19%) | 12/56 (21.4%) | 0/5 (0%) | 6/18 (33.3%) | 2/16 (12.5%) | 4/22 (18.2%) |
 IgG + IgM | Samples | 2/63 (3.2%) | 2/56 (3.6%) | 0/5 (0%) |  |  |  |
 IgG + IgA | Samples | 4/63 (6.3%) | 4/56 (7.1%) | 0/5 (0%) |  |  |  |
 IgM + IgA | Samples | 6/63 (9.5%) | 6/56 (10.7%) | 0/5 (0%) |  |  |  |
1-class reaction | Samples | 13/63 (20.6%) | 11/56 (19.6%) | 1/5 (20%) | 6/18 (33.3%) | 3/16 (18.8%) | 2/22 (9.1%) |
 Only IgG | Samples | 4/63 (6.3%) | 3/56 (5.4%) | 0/5 (0%) |  |  |  |
 Only IgM | Samples | 5/63 (7.9%) | 5/56 (8.9%) | 0/5 (0%) |  |  |  |
 Only IgA | Samples | 4/63 (6.3%) | 3/56 (5.4%) | 1/5 (20%) |  |  |  |
b. Based on Ig-IF > 10% | |||||||
3-class reactiona | Samples | 2/63 (3.2%) | 2/56 (3.6%) | 0/5 (0%) | 1/18 (5.6%) | 0/16 (0%) | 1/22 (4.5%) |
2-class reactionb | Samples | 6/63 (9.5%) | 6/56 (10.7%) | 0/5 (0%) | 2/18 (11.1%) | 1/16 (6.3%) | 3/22 (13.6%) |
 IgG + IgM | Samples | 0/63 (0%) | 0/56 (0%) | 0/5 (0%) |  |  |  |
 IgG + IgA | Samples | 1/63 (1.6%) | 1/56 (1.8%) | 0/5 (0%) |  |  |  |
 IgM + IgA | Samples | 5/63 (7.9%) | 5/56 (8.9%) | 0/5 (0%) |  |  |  |
1-class reaction | Samples | 13/63 (20.6%) | 13/56 (23.2%) | 0/5 (0%) | 9/18 (50%) | 3/16 (18.8%) | 1/22 (4.5%) |
 Only IgG | Samples | 3/63 (4.8%) | 3/56 (5.4%) | 0/5 (0%) |  |  |  |
 Only IgM | Samples | 6/63 (9.5%) | 6/56 (10.7%) | 0/5 (0%) |  |  |  |
 Only IgA | Samples | 4/63 (6.3%) | 4/56 (7.1%) | 0/5 (0%) |  |  |  |