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Table 7 CSF findings at the time of the first LP and at follow-up LP. To control for the fact that the number of CSF samples obtained per event differed among patients in the subgroup with follow-up LPs, only the first LP obtained during each attack was taken into account for this analysis

From: Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients

 

Units

First LP ever

Follow-up LPs, first LP/event

Pleocytosis, all acute attacks

Samples

41/70 (58.6%)

4/11 (36.4%)

Pleocytosis, acute MY

Samples

21/25 (84%)

1/2 (50%)

Pleocytosis, acute ON

Samples

4/21 (19%)

1/4 (25%)

Pleocytosis, acute BRAIN

Samples

16/24 (66.7%)

2/5 (40%)

OCB, all acute attacks

Samples

8/67 (11.9%)

1/12 (8.3%)

OCB, acute MY

Samples

6/25 (24%)

1/2 (50%)a

OCB, acute ON

Samples

0/21 (0%)

0/5 (0%)

OCB, acute BRAIN

Samples

2/21 (9.5%)

0/5 (0%)

IgG-IF > 10%, all acute attacks

Samples

4/53 (7.5%)

6/12 (50%)

IgG-IF > 10%, acute MY

Samples

2/20 (10%)

1/1 (100%)

IgG-IF > 10%, acute ON

Samples

0/18 (0%)

0/1 (0%)

IgG-IF > 10%, acute BRAIN

Samples

2/15 (13.3%)

0/5 (0%)

QAlb > Qlim(Alb), all acute attacks

Samples

28/56 (50%)

3/8 (37.5%)

QAlb > Qlim(Alb), acute MY

Samples

14/21 (66.7%)

0/1 (0%)

QAlb > Qlim(Alb), acute ON

Samples

3/18 (16.7%)

2/2 (100%)

QAlb > Qlim(Alb), acute BRAIN

Samples

11/17 (64.7%)

1/5 (20%)

CSF TP elevated, all acute attacks

Samples

16/66 (24.2%)

2/11 (18.2%)

CSF TP elevated, acute MY

Samples

9/23 (39.1%)

1/2 (50%)

CSF TP elevated, acute ON

Samples

1/20 (5%)

0/4 (0%)

CSF TP elevated, acute BRAIN

Samples

6/23 (26.1%)

1/5 (20%)

CSF l-lactate elevated, all acute attacks

Samples

17/49 (34.7%)

2/10 (20%)

CSF l-lactate elevated, acute MY

Samples

9/18 (50%)

1/2 (50%)

CSF l-lactate elevated, acute ON

Samples

2/16 (12.5%)

1/4 (25%)

CSF l-lactate elevated, acute BRAIN

Samples

6/15 (40%)

0/4 (0%)

Time since attack onset, acute LPs

Days

2 (0–33)

4.5 (0–40)

  1. IgG-IF intrathecal IgG fraction, OCB oligoclonal bands, QAlb CSF/serum albumin quotient, TP total protein, WCC white cell count
  2. ap = n.s.