Fig. 1From: Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout miceFKN is expressed in brain tissue following tail vein injection of adeno-associated viral vector (AAV). Quantitative assessment of FKN expression in brain homogenates. Animals were sacrificed, and brain tissue was collected for analysis by ELISA. CX3CL1−/− mice treated with GFP displayed negligible levels of FKN expression in brain while mice injected with AAV expressing mFKN displayed expression levels similar to that of WT mice. Animals receiving AAV expressing sFKN demonstrated high levels of expression in comparison to WT controls. Data were analyzed by one-way ANOVA (n = 4, F (3, 13) = 22.85; p < 0.0001) with Tukey’s post hoc test. *p < 0.05, **p < 0.01, and ***p < 0.001Back to article page