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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

Fig. 3

Effect of STING on brain edema and short-term neurological function. a Representative picture and quantitative analysis of phosphorylation level of TBK1, the direct substrate of STING, in different groups. n = 6. b Quantification of SAH grade. n = 24. c Representative HE staining images of brain slides. No identifiable morphologic differences between sham-treated and SAH mice were noted under light microscope. Red circle shows the region of brain section collected for western blotting, immunofluorescence staining, and Nissl staining in cortex. n = 6. d Quantification of brain water content. n = 6. e-g Quantification of neurological function with two different scoring systems at 24 h (n = 24) and 72 h (n = 10) after SAH. Data are represented as mean ± SD. *P < 0.05 versus sham group. #P < 0.05 versus SAH + vehicle group

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