Fig. 5

Change in expression of EPO in cultured astrocytes during hypothermia following oxygen/glucose deprivation (OGD). a Schematic representation of the experimental groups. b Time course of the change in expression of EPO mRNA. Data are the mean ± SEM (n=3 in each group). ^‡P < 0.05 compared with the control→37 °C group. ^*P < 0.05 compared with the control→33.5 °C group. ^#P < 0.05 compared with the OGD→37 °C group. c Effect of hypothermia following OGD on EPO protein concentration in conditioned medium. EPO protein concentrations were measured in astrocyte-conditioned medium during 24 h of hypothermia, following the medium change after OGD. N.D., not detected. Data are the mean ± SEM (n=6 in each group). ^#P < 0.05 compared with the OGD→37 °C group