Fig. 3
From: Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats
Effects of microglia depletion induced by administration of diphtheria toxin to Cx3cr1-Dtr transgenic rats on the neuroinflammatory response to LPS in the hypothalamus and liver. LPS (0.5 mg/kg) was administered 48 h after diphteria toxin was given to ablate microglia, and tissue samples were collected 24 h later. Mean ± SEM, n = 4–8/group, *p < 0.05, **p < 0.01, ***p < 0/001