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Table 4 Effects of PLX on body weight, locomotor activity in a new cage, and voluntary wheel running response to LPS. F values from 2 (PLX diet vs. control diet) × time ANOVA for body weight and voluntary wheel running before LPS treatment, from 2 (PLX diet vs. control diet) × 2 (LPS vs. control) ANOVA for locomotor activity in a new cage, and from 2 (PLX diet vs. control diet) × 2 (LPS vs. control) ANOVA with 6 mice/group with time as a repeated factor for body weight loss and voluntary wheel running

From: Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats

  PLX LPS PLX × LPS Time PLX × time LPS × time PLX × LPS × time
Body weight F(1, 22) = 0.200 NS    F(6, 132) = 3.85** F(6, 132) = 1.86 NS   
LPS effect on body weight F(1, 20) = 0.342 NS F(1, 20) = 1.14 NS F(1, 20) = 1.31 NS F(2, 40) = 65.2*** F(2, 40) = 1.57 NS F(2, 40) = 31.0*** F(2, 40) = 1.57 NS
LPS effect on activity new cage F(1, 20) = 0.186 NS F(1, 20) = 16.8*** F(1, 20) = 1.36 NS     
Pre-LPS wheel running F(1, 22) = 18.4***    F(6, 132) = 44.3*** F(6, 132) = 0.803 NS   
LPS effect on wheel running F(1, 20) = 275*** F(1, 20) = 7.45* F(1, 20) = 1.67 NS   F(5, 100) = 4.24** F(5, 100) = 25.8*** F(5, 100) = 7.90***
  1. NS non-significant
  2. *p < 0.05, **p < 0.01, ***p < 0.001