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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: NT-4 attenuates neuroinflammation via TrkB/PI3K/FoxO1 pathway after germinal matrix hemorrhage in neonatal rats

Fig. 3

The increase of exogenous NT-4 in the brain and immunofluorescence double staining results. a Western blot results of recombinant human NT-4 concentration in the sham group, vehicle group, and NT-4 group. Asterisk indicates p < 0.05 vs sham, number sign indicates p < 0.05 vs GMH + vehicle, One-way ANOVA, Tukey’s test, n = 6/group. Data is presented as mean ± SD. b Brain sample with schematic illustration showing the area in the perihematomal region (indicated by red square) from where the images were taken for immunofluorescence staining. c Immunofluorescence co-localization of TrkB with microglia (Iba-1), neurons (NeuN), and astrocytes (GFAP) on day 3 after GMH. (n = 2. Scale bar = 50 μm.)

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