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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat

Fig. 4

Effect of DHLA on ROS/NLRP3/caspase-1/IL-1β signaling pathway in rats. a Representative Western blot bands in the hippocampal region. b–d Statistical graphs of relative protein expression of NLRP3 (b), caspase-1 (c), and IL-1β (d). e ROS expression in the hippocampal. The data were expressed as means ± SEM (n = 6). ***P < 0.001; ****P < 0.0001 versus the control group. #P < 0.05; ##P < 0.01; ###P < 0.001 versus the LPS group. The Shapiro-Wilk test results showed that all the data are normally distributed (p > 0.05)

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Journal of Neuroinflammation

ISSN: 1742-2094