Fig. 9

The effects of cytokines on neuronal cytolysis induced by conditioned media from microglias. Note that the cytolysis of cerebral cortical neurons (a) and cerebellar neurons (b) induced by conditioned media from microglias preincubated with OMS + NB IgG was not influenced by IL-1β, and the cytolysis of cerebral cortical neurons (c) and cerebellar neurons (d) was also not changed by IL-6. Consistently, the cytolysis of cerebral cortical neurons (e) and cerebellar neurons (f) was not affected by TNF-α, and the cytolysis of cerebral cortical neurons (g) and cerebellar neurons (h) was not changed by MCP-1. p > 0.05; 0.1% BSA, OMS + NB vs cytokine, OMS + NB. ^***p < 0.001; 0.1% BSA, NB vs cytokine, NB. One-way ANOVA, n = 20 (0.1% BSA, NB; cytokine, NB), n = 10 (0.1% BSA, OMS + NB; cytokine, OMS + NB)